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Key Points Question Do associations between prenatal dietary inflammation and child adiposity trajectories differ by levels of psychosocial stress in pregnancy? Findings In this cohort study of 1060 mother-child dyads,… Click to show full abstract
Key Points Question Do associations between prenatal dietary inflammation and child adiposity trajectories differ by levels of psychosocial stress in pregnancy? Findings In this cohort study of 1060 mother-child dyads, children exposed to the highest vs lowest quartile of diet-associated inflammation in utero experienced faster adiposity accrual from childhood to adolescence. Maternal depressive symptoms and social vulnerabilities during pregnancy strengthened these associations. Meaning The findings of this study suggest that children exposed to poor prenatal dietary quality with high inflammatory potential in the presence of psychosocial stressors in utero may sustain worse adiposity outcomes lasting until adolescence.
Journal Title: JAMA Network Open
Year Published: 2023
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