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Effect of Androgen Suppression on Clinical Outcomes in Hospitalized Men With COVID-19

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Key Points Question Does androgen suppression improve clinical outcomes in hospitalized men with COVID-19? Findings In this randomized clinical trial including 96 men, androgen suppression with the addition of degarelix… Click to show full abstract

Key Points Question Does androgen suppression improve clinical outcomes in hospitalized men with COVID-19? Findings In this randomized clinical trial including 96 men, androgen suppression with the addition of degarelix vs placebo plus standard care did not show reduction of the composite end point of mortality, ongoing hospitalization, or requirement for mechanical ventilation at day 15 after randomization. Meaning This randomized clinical trial found that androgen suppression did not improve outcomes in men hospitalized for COVID-19.

Keywords: clinical outcomes; outcomes hospitalized; hospitalized men; androgen suppression; suppression

Journal Title: JAMA Network Open
Year Published: 2022

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