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Association of Perinatal and Childhood Ischemic Stroke With Attention-Deficit/Hyperactivity Disorder

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Key Points Question Does the risk of attention-deficit/hyperactivity disorder (ADHD) increase after pediatric stroke, and is that risk associated with family history of ADHD, adverse motor outcomes, or comorbid epilepsy?… Click to show full abstract

Key Points Question Does the risk of attention-deficit/hyperactivity disorder (ADHD) increase after pediatric stroke, and is that risk associated with family history of ADHD, adverse motor outcomes, or comorbid epilepsy? Findings This nationwide cohort study of 1320 patients who had perinatal or childhood stroke and 13 141 matched controls found a 2-fold increased risk of ADHD after stroke. Development of adverse motor outcomes and/or epilepsy were associated with a further elevated risk in children with perinatal stroke. Meaning These findings suggest that children may face an increased risk of ADHD after stroke and that surveillance for ADHD should be considered by pediatricians performing follow-up of children with pediatric stroke.

Keywords: hyperactivity disorder; attention deficit; risk; perinatal childhood; deficit hyperactivity

Journal Title: JAMA Network Open
Year Published: 2022

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