LAUSR

Key Points Question What were the patterns of proton beam therapy (PBT) use among groups of patients with different PBT indications in the US from 2014 to 2018? Findings In this cross-sectional study with 5 919 368 patients, PBT use increased nationally between 2004 and 2018 for both cancer sites for which PBT use is the recommended treatment modality (group 1) and for sites for which effectiveness of PBT over other radiotherapy modalities is still being investigated (group 2). Breast and prostate cancers are most frequently treated with PBT. Meaning The findings of this study suggest that PBT uptake varies by indication group and is most commonly used to treat cancers for which PBT effectiveness is still under study.