LAUSR

Key Points Question What are the rates and associated patient characteristics of discontinuation of antipsychotic medications (APMs) among older adults following infection-related hospitalization? Findings In this cohort study of 5835 patients in the US, we observed discontinuation rates of only 11% for new atypical APM users and 52% for new haloperidol users by 30 days after initiation following infection-related hospitalization. Dementia and prolonged hospitalization were inversely associated with haloperidol and atypical APM discontinuation. Meaning These findings suggest that contrary to clinical recommendations, APM discontinuation rates following infection-related hospitalization are low and are lower for atypical APMs than for haloperidol.