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Key Points Question Do household income levels factor into 21-gene recurrence score (RS) and mortality among patients with estrogen receptor (ER)-positive breast cancer? Findings In this cohort study involving 119 478… Click to show full abstract
Key Points Question Do household income levels factor into 21-gene recurrence score (RS) and mortality among patients with estrogen receptor (ER)-positive breast cancer? Findings In this cohort study involving 119 478 women, low income was associated with higher RS and worse survival. On subgroup analysis, similar findings were observed among those with RS below 26, while there was no survival difference between income levels among others with scores 26 or higher. Meaning These results suggest that low household income is associated with more aggressive tumor biology and significantly worse mortality among those with RS below 26.
Journal Title: JAMA Network Open
Year Published: 2023
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