LAUSR

Key Points Question How are sex disparities in nonacceptance of statin therapy associated with control of low-density lipoprotein (LDL) cholesterol levels? Findings In this cohort study of 24 212 adults at high cardiovascular risk, patients who accepted a statin therapy recommendation by their clinicians achieved an LDL cholesterol level of less than 100 mg/dL in a median time of 1.5 years vs 4.4 years for patients who did not accept statin therapy. Women were significantly less likely than men to accept statin therapy recommendations and achieve an LDL cholesterol level of less than 100 mg/dL. Meaning This study suggests that patients who do not accept statin therapy have significantly higher LDL cholesterol levels; sex disparities in statin acceptance could be associated with cardiovascular risk for women.