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Clinical Outcomes Following Treatment for COVID-19 With Nirmatrelvir/Ritonavir and Molnupiravir Among Patients Living in Nursing Homes

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Key Points Question What is the association between the use of 2 oral antivirals, molnupiravir and nirmatrelvir/ritonavir, and the risk of hospitalization and inpatient disease progression among patients with COVID-19… Click to show full abstract

Key Points Question What is the association between the use of 2 oral antivirals, molnupiravir and nirmatrelvir/ritonavir, and the risk of hospitalization and inpatient disease progression among patients with COVID-19 living in nursing homes? Findings In this cohort study of 14 617 patients, both molnupiravir and nirmatrelvir/ritonavir treatment were associated with a lower risk of hospitalization and a lower risk of inpatient disease progression. Meaning These findings suggest that the use of oral antivirals to treat COVID-19 may benefit older patients living in nursing homes by decreasing risks of hospitalization and inpatient disease progression.

Keywords: nursing homes; patients living; nirmatrelvir ritonavir; living nursing; among patients

Journal Title: JAMA Network Open
Year Published: 2023

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