LAUSR

Key Points Question Does a multimodal model combining perinatal, postnatal, and brain structure and function risk factors improve the prediction of death or neurodevelopmental impairment at age 2 years in extremely preterm infants? Findings In a prognostic study including 109 extremely preterm newborns, multimodal processing of perinatal, postnatal, and brain structure and function risk factors significantly improved the prediction of 2-year outcome compared with unimodal models in which risk factors were processed independently. Meaning This model for prediction of outcomes for extremely preterm newborns may be useful as a decision support tool in critical care management.