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Key Points Question Is fluoropyrimidine-based systemic chemotherapy effective in treating patients with inoperable low-grade mucinous appendiceal adenocarcinoma? Findings In this randomized crossover trial that included 24 patients, there was no… Click to show full abstract
Key Points Question Is fluoropyrimidine-based systemic chemotherapy effective in treating patients with inoperable low-grade mucinous appendiceal adenocarcinoma? Findings In this randomized crossover trial that included 24 patients, there was no significant difference in tumor growth between treatment and observation time periods. Meaning These findings suggest that patients with low-grade mucinous appendiceal adenocarcinoma did not derive clinically meaningful benefit from systemic fluoropyrimidine-based chemotherapy.
Journal Title: JAMA Network Open
Year Published: 2023
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