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Key Points Question As a biomarker of biological aging, does DNA methylation (DNAm) adequately assess the rate of change in aging over time among socioeconomically diverse middle-aged African American and… Click to show full abstract
Key Points Question As a biomarker of biological aging, does DNA methylation (DNAm) adequately assess the rate of change in aging over time among socioeconomically diverse middle-aged African American and White adults? Findings In this cohort study of 470 socioeconomically diverse middle-aged African American and White adults, household income below poverty level and African American race were associated with a higher DNAm-based pace of aging. Meaning These findings suggest that the DNAm-based pace of aging may provide insight into how social constructs such as race play a role in healthy aging.
Journal Title: JAMA Network Open
Year Published: 2023
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