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Assessment of Neurodevelopment in Infants With and Without Exposure to Asymptomatic or Mild Maternal SARS-CoV-2 Infection During Pregnancy

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Key Points Question Is asymptomatic or mild maternal SARS-CoV-2 infection compared with no infection during pregnancy associated with observable infant neurodevelopmental differences at ages 5 to 11 months? Findings In… Click to show full abstract

Key Points Question Is asymptomatic or mild maternal SARS-CoV-2 infection compared with no infection during pregnancy associated with observable infant neurodevelopmental differences at ages 5 to 11 months? Findings In this cohort study involving a geographically diverse cohort of 407 infants born to 403 mothers, no association was found between mild or asymptomatic maternal SARS-CoV-2 infection during pregnancy and infant cognition, language, or motor development as assessed by a novel telehealth-adapted version of the Developmental Assessment of Young Children, second edition. Meaning Given the continued high prevalence of SARS-CoV-2 infection globally, these data offer information regarding infant neurodevelopment that may be helpful for pregnant individuals with asymptomatic or mild SARS-CoV-2 infections.

Keywords: maternal sars; infection pregnancy; infection; asymptomatic mild; cov infection; sars cov

Journal Title: JAMA Network Open
Year Published: 2023

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