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Association of Amyloid Reduction After Donanemab Treatment With Tau Pathology and Clinical Outcomes

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This post hoc analysis of the randomized clinical trial, Study of LY3002813 in Participants With Early Symptomatic Alzheimer’s Disease (TRAILBLAZER-ALZ), investigates if amyloid reduction from donanemab treatment is associated with… Click to show full abstract

This post hoc analysis of the randomized clinical trial, Study of LY3002813 in Participants With Early Symptomatic Alzheimer’s Disease (TRAILBLAZER-ALZ), investigates if amyloid reduction from donanemab treatment is associated with slowing of tau pathology and clinical decline in individuals with early symptomatic Alzheimer disease.

Keywords: reduction donanemab; donanemab treatment; amyloid reduction; pathology; tau pathology; pathology clinical

Journal Title: JAMA Neurology
Year Published: 2022

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