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Ocular Toxicity of Mitogen-Activated Protein Kinase Inhibitors

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Ocular Toxicity of Mitogen-Activated Protein Kinase Inhibitors The Oxford Eye Hospital and the Oxford Experimental Cancer Centre collaborate in monitoring patients in a number of early-phase clinical trials. In this… Click to show full abstract

Ocular Toxicity of Mitogen-Activated Protein Kinase Inhibitors The Oxford Eye Hospital and the Oxford Experimental Cancer Centre collaborate in monitoring patients in a number of early-phase clinical trials. In this study, we report the ocular toxic effects of 3 different mitogen-activated protein kinase inhibitors (MEKIs) currently at independent stages of clinical development, including ongoing studies.

Keywords: kinase inhibitors; protein kinase; mitogen activated; activated protein

Journal Title: JAMA Oncology
Year Published: 2017

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