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Patient Preference and Treatment Satisfaction With a Port Delivery System for Ranibizumab vs Intravitreal Injections in Patients With Neovascular Age-Related Macular Degeneration

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Key Points Question Do patients with neovascular age-related macular degeneration (nAMD) treated with a surgically implanted port delivery system (PDS) with ranibizumab prefer the PDS over intravitreal injections of anti–vascular… Click to show full abstract

Key Points Question Do patients with neovascular age-related macular degeneration (nAMD) treated with a surgically implanted port delivery system (PDS) with ranibizumab prefer the PDS over intravitreal injections of anti–vascular endothelial growth factor agents? Findings This phase 3 randomized clinical trial found that treatment satisfaction was high with both PDS and intravitreal treatment, but almost all patients in the PDS arm preferred treatment delivered via the PDS at week 40 vs previous intravitreal injections. Meaning Although PDS treatment was preferred by most patients assigned to PDS over previous intravitreal injections, both delivery methods have high treatment satisfaction.

Keywords: patients neovascular; treatment satisfaction; intravitreal injections; treatment; delivery

Journal Title: JAMA Ophthalmology
Year Published: 2022

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