LAUSR

Key Points Question What is the effectiveness of cognitive remediation on cognition and functioning in people diagnosed with schizophrenia, and what are its active ingredients? Findings In this systematic review and meta-analysis, cognitive remediation was confirmed as effective on both cognitive and functional outcomes and potentially useful for all patients with schizophrenia, even those most severely affected. An active and trained therapist, structured development of cognitive strategies, and integration with rehabilitation were crucial ingredients of efficacy. Meaning This analysis demonstrates that cognitive remediation is an evidence-based intervention, which should be recommended and implemented more widely in the standard treatment of schizophrenia.