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Key Points Question Do mental disorders antedate dementia in the population? Findings In this population-based administrative register study of 1.7 million New Zealand citizens observed for 3 decades, people with… Click to show full abstract
Key Points Question Do mental disorders antedate dementia in the population? Findings In this population-based administrative register study of 1.7 million New Zealand citizens observed for 3 decades, people with early-life mental disorders were at elevated risk of subsequent dementia and younger dementia onset. Associations were evident across different psychiatric conditions, for Alzheimer disease and all other dementias, and after accounting for preexisting physical diseases and socioeconomic deprivation. Meaning Findings from this study suggest that ameliorating mental disorders in early life might reduce risk of cognitive decline and neurodegenerative disease in later life.
Journal Title: JAMA Psychiatry
Year Published: 2022
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