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Epidemiologic and Genetic Associations of Endometriosis With Depression, Anxiety, and Eating Disorders

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Key Points Question What biological mechanisms are associated with endometriosis with mental health comorbidities? Findings This genetic association study of 8276 women with endometriosis and 194 000 female controls found… Click to show full abstract

Key Points Question What biological mechanisms are associated with endometriosis with mental health comorbidities? Findings This genetic association study of 8276 women with endometriosis and 194 000 female controls found that pleiotropy is likely associated with the comorbid depression, anxiety, and eating disorders observed in patients with endometriosis. Meaning This study highlights the importance of considering endometriosis pathogenesis from a more comprehensive perspective, including both mental and physical health.

Keywords: depression anxiety; eating disorders; endometriosis; anxiety eating

Journal Title: JAMA Network Open
Year Published: 2023

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