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Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats

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Whether activation or inhibition of the mTOR pathway is beneficial to ischemic injury remains controversial. It may result from the different reaction of ischemic penumbra and core to modulation of… Click to show full abstract

Whether activation or inhibition of the mTOR pathway is beneficial to ischemic injury remains controversial. It may result from the different reaction of ischemic penumbra and core to modulation of mTOR pathway after cerebral ischemia–reperfusion injury in rats.

Keywords: modulating apoptosis; stroke modulating; rapamycin prevents; penumbra; prevents cerebral; cerebral stroke

Journal Title: Annals of Clinical and Translational Neurology
Year Published: 2018

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