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Effects of antiepileptic drugs in a new TSC/mTOR‐dependent epilepsy mouse model

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An epilepsy mouse model for Tuberous Sclerosis Complex (TSC) was developed and validated to investigate the mechanisms underlying epileptogenesis. Furthermore, the possible antiepileptogenic properties of commonly used antiepileptic drugs (AEDs)… Click to show full abstract

An epilepsy mouse model for Tuberous Sclerosis Complex (TSC) was developed and validated to investigate the mechanisms underlying epileptogenesis. Furthermore, the possible antiepileptogenic properties of commonly used antiepileptic drugs (AEDs) and new compounds were assessed.

Keywords: antiepileptic drugs; mouse model; epilepsy mouse

Journal Title: Annals of Clinical and Translational Neurology
Year Published: 2019

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