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Translocator protein in late stage Alzheimer’s disease and Dementia with Lewy bodies brains

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Increased translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor (PBR), in glial cells of the brain has been used as a neuroinflammation marker in the early and middle… Click to show full abstract

Increased translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor (PBR), in glial cells of the brain has been used as a neuroinflammation marker in the early and middle stages of neurodegenerative diseases, such as Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB). In this study, we investigated the changes in TSPO density with respect to late stage AD and DLB.

Keywords: lewy bodies; dementia lewy; late stage; alzheimer disease; disease dementia; translocator protein

Journal Title: Annals of Clinical and Translational Neurology
Year Published: 2019

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