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Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers

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Numerous investigators have theorized that postoperative changes in Alzheimer's disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we determined the relationship between postoperative changes in cognition and cerebrospinal (CSF) tau,… Click to show full abstract

Numerous investigators have theorized that postoperative changes in Alzheimer's disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we determined the relationship between postoperative changes in cognition and cerebrospinal (CSF) tau, p‐tau‐181p, or Aβ levels after non‐cardiac, non‐neurologic surgery in older adults.

Keywords: fluid neurodegenerative; changes cognition; postoperative changes; disease; cerebrospinal fluid; cognition cerebrospinal

Journal Title: Annals of Clinical and Translational Neurology
Year Published: 2022

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