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Antagonist of Chrna1 prevents the pathogenesis of primary focal hyperhidrosis

Primary focal hyperhidrosis (PFH) is an autonomic neurological disease in which exocrine glands are oversecreted due to autonomic dysfunction of the sympathetic nervous system. Chrna1 promotes the pathogenesis of PFH.… Click to show full abstract

Primary focal hyperhidrosis (PFH) is an autonomic neurological disease in which exocrine glands are oversecreted due to autonomic dysfunction of the sympathetic nervous system. Chrna1 promotes the pathogenesis of PFH. We aimed to check if downregulating of Chrna1 by cisatracurium could alleviate the symptoms of PFH.

Keywords: focal hyperhidrosis; primary focal; antagonist chrna1; chrna1 prevents

Journal Title: Annals of Clinical and Translational Neurology
Year Published: 2022

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