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Comparison of plasma and CSF biomarkers in predicting cognitive decline

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Concentrations of amyloid‐β peptides (Aβ42/Aβ40) and neurofilament light (NfL) can be measured in plasma or cerebrospinal fluid (CSF) and are associated with Alzheimer’s disease brain pathology and cognitive impairment. This… Click to show full abstract

Concentrations of amyloid‐β peptides (Aβ42/Aβ40) and neurofilament light (NfL) can be measured in plasma or cerebrospinal fluid (CSF) and are associated with Alzheimer’s disease brain pathology and cognitive impairment. This study directly compared plasma and CSF measures of Aβ42/Aβ40 and NfL as predictors of cognitive decline.

Keywords: plasma csf; cognitive decline; csf; comparison plasma

Journal Title: Annals of Clinical and Translational Neurology
Year Published: 2022

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