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CSF glial markers are elevated in a subset of patients with genetic frontotemporal dementia

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Neuroinflammation has been shown to be an important pathophysiological disease mechanism in frontotemporal dementia (FTD). This includes activation of microglia, a process that can be measured in life through assaying… Click to show full abstract

Neuroinflammation has been shown to be an important pathophysiological disease mechanism in frontotemporal dementia (FTD). This includes activation of microglia, a process that can be measured in life through assaying different glia‐derived biomarkers in cerebrospinal fluid. However, only a few studies so far have taken place in FTD, and even fewer focusing on the genetic forms of FTD.

Keywords: elevated subset; markers elevated; glial markers; dementia; frontotemporal dementia; csf glial

Journal Title: Annals of Clinical and Translational Neurology
Year Published: 2022

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