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Plasma phosphorylated tau181 predicts cognitive and functional decline

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To determine if plasma tau phosphorylated at threonine 181 (p‐tau181) distinguishes pathology‐confirmed Alzheimer's disease (AD) from normal cognition (NC) adults, to test if p‐tau181 predicts cognitive and functional decline, and… Click to show full abstract

To determine if plasma tau phosphorylated at threonine 181 (p‐tau181) distinguishes pathology‐confirmed Alzheimer's disease (AD) from normal cognition (NC) adults, to test if p‐tau181 predicts cognitive and functional decline, and to validate findings in an external cohort.

Keywords: cognitive functional; predicts cognitive; tau181 predicts; plasma; functional decline

Journal Title: Annals of Clinical and Translational Neurology
Year Published: 2022

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