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An image‐based model of brain volume biomarker changes in Huntington's disease

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Determining the sequence in which Huntington's disease biomarkers become abnormal can provide important insights into the disease progression and a quantitative tool for patient stratification. Here, we construct and present… Click to show full abstract

Determining the sequence in which Huntington's disease biomarkers become abnormal can provide important insights into the disease progression and a quantitative tool for patient stratification. Here, we construct and present a uniquely fine‐grained model of temporal progression of Huntington's disease from premanifest through to manifest stages.

Keywords: image based; huntington disease; disease; model brain; based model

Journal Title: Annals of Clinical and Translational Neurology
Year Published: 2018

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