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co-workers show how bioengineering of mycobacterial antigens enhances their intermolecular interactions that mediate self-assembly of discrete antigen particles, inside a safe bacterial cell factory, Escherichia coli. The resulting pure antigen… Click to show full abstract
co-workers show how bioengineering of mycobacterial antigens enhances their intermolecular interactions that mediate self-assembly of discrete antigen particles, inside a safe bacterial cell factory, Escherichia coli. The resulting pure antigen particles induce strong antigen-specific humoral and cell-mediated immune responses. This innovative bioengineering approach enables rapid development of custom-made particulate vaccines with augmented immunological properties toward induction of protective immunity. Particulate Vaccines
Journal Title: Advanced Biosystems
Year Published: 2018
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