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Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response

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A fiber composite system is presented which recapitulates the fiber‐composite‐like nature of tissues and generates similar modes of shear and tension. The shear/tension ratio can be customized during composite manufacture… Click to show full abstract

A fiber composite system is presented which recapitulates the fiber‐composite‐like nature of tissues and generates similar modes of shear and tension. The shear/tension ratio can be customized during composite manufacture and incorporates viable cells. The system is a valuable tool for mechanotransduction research, providing a platform with physiologically relevant conditions for investigating cell behavior in different tissue types.

Keywords: tension shear; behavior tension; micromechanical behavior; recapitulating micromechanical; shear biomimetic; tension

Journal Title: Advanced Healthcare Materials
Year Published: 2017

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