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The Efficient Regeneration of Corneal Nerves via Tunable Transmembrane Signaling Channels Using A Transparent Graphene-based Corneal Stimulation Electrode.

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The efficient regeneration of corneal nerves is of limited in the field of ophthalmology. This work reports the use of a non-invasive electrical stimulation technique that uses a transparent graphene-based… Click to show full abstract

The efficient regeneration of corneal nerves is of limited in the field of ophthalmology. This work reports the use of a non-invasive electrical stimulation technique that uses a transparent graphene-based corneal stimulation electrode and that can achieve efficient regeneration of corneal nerves. The corneal stimulation electrode was prepared using electroactive nitrogen-containing conducting polymers such as polyaniline functionalized graphene (PAG). This composite can carry a high capacitive current. It can be used to tune transmembrane signaling pathways including calcium channels and the MAPK signaling pathway. Tuning can lead to the efficient regeneration of corneal damaged nerves after the surgery of laser in-situ keratomileusis (LASIK). The composite and its application reported have the potential to provide a new way to treat nerve-related injuries. This article is protected by copyright. All rights reserved.

Keywords: corneal nerves; efficient regeneration; regeneration corneal; stimulation

Journal Title: Advanced healthcare materials
Year Published: 2022

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