LAUSR

Here, tris(hydroxymethyl)aminomethane (i.e., Tris) is reported to be an effective protecting agent to stabilize 2D nanomaterials in water for various enhanced applications. As demonstrated, molybdenum sulfide (MoS2) nanosheets are first exfoliated from MoS2 bulk under a low‐energy sonication in the assistance of protein bovine serum albumin (BSA), and then BSA molecules are replaced with Tris to stabilize the exfoliated MoS2 nanosheets. The Tris‐stabilized MoS2 nanosheets have a robust dispersibility to resist long‐term storage (e.g., 2.5 years), high temperature (e.g., 220 °C), and high speed centrifugation (e.g., 12 000 rpm). Furthermore, they also exhibit high biocompatibility and promising photothermal effect, which provide a better performance in photothermal therapy for inhibiting the growth of tumor. In addition, the surface Tris molecules readily introduce the grafting of polydopamine on MoS2 nanosheets to form a universal platform for coating of other functional polymers on nanosheets. Overall, this work not only brings more opportunities to exploit the outstanding applications of 2D nanomaterials, but also suggests a new and effective route to prepare the composite of nanosheets and functional polymers for their synergistic properties.