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DOI: 10.1002/advs.201802184 But it is not only an increase in quantity that we have experienced. The variety of topics has broadened as well: initially dominated by materials science research, other communities have now discovered Advanced Science as an attractive publishing platform. In order to additionally promote this content and help guide interested readers to the bio and life scienceoriented content, we recently launched our Health, Medical, and Life Sciences Virtual Issue. Updated on a regular basis, this ongoing series contains an editorial choice of our favorite articles in areas like CRISPR, cancer therapy, synthetic biology, and antibacterial hydrogels. Maybe next year’s top cited papers (Table 1) will contain more of these topics as well. On the occasion of the journal’s 5th anniversary that is approaching in December of this year, we have started a cele­ bratory series of invited-only articles from our executive advisory board members, providing both an overview of progress, and, importantly, insight into possible future directions of their Welcome to the 6th volume of Advanced Science. Like in previous years, there is so much positive news to spread for Advanced Science. All key performance indicators that characterize a flourishing journal show a very positive trend (Figure 1). Our content is popular like never before–the number of full text downloads increased by another 40% in 2018. Looking at the number of total citations in 2018 makes us optimistic that we will see another increase in the impact factor in 2019. The number of submissions had already been high and growing steadily during the first half of the year 2018. After the announcement of the new impact factor of 12.441 (+40%), we saw another big jump in the number of papers submitted. We continue to select the best papers following our strict and rigorous peer-review process. Still, the number of published articles is growing as well. While the submissions have more than doubled in 2018, we published about 60% more compared to 2017. This year we will therefore publish biweekly issues.