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A tumor vascular‐targeted interlocking trimodal nanosystem that induces and exploits hypoxia is described by Hong‐Zhuan Chen, Chao Fang, and co‐workers in article number https://doi.org/10.1002/advs.201800034. In the image, the two streams… Click to show full abstract
A tumor vascular‐targeted interlocking trimodal nanosystem that induces and exploits hypoxia is described by Hong‐Zhuan Chen, Chao Fang, and co‐workers in article number https://doi.org/10.1002/advs.201800034. In the image, the two streams of water from bamboo pipes and the rotary waterwheel are shown to represent verteporfin for vascular‐targeted photodynamic treatment and HIF‐1α siRNA for elevated activating reductases (CYP450), which can trigger the activation of AQ4N (a hypoxia‐activated prodrug).
Journal Title: Advanced Science
Year Published: 2018
Link to full text (if available)
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