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Malic Enzyme 1 In article number 2205436, Xuexian Fang, Fudi Wang, and co‐workers discover Malic Enzyme 1 (ME1) as a novel ferroptosis inhibitory gene, which protects the liver function against… Click to show full abstract
Malic Enzyme 1 In article number 2205436, Xuexian Fang, Fudi Wang, and co‐workers discover Malic Enzyme 1 (ME1) as a novel ferroptosis inhibitory gene, which protects the liver function against ischemia/reperfusion (I/R) injury. The design is inspired by General Yue Fei (represents ME1), a national hero in the Song Dynasty (960‐1279) who accomplished great feats in many battles (represents ferroptosis‐induced liver injury during the process of I/R). This work provides a novel target and mechanistic insight into ferroptosis induced liver injury.
Journal Title: Advanced Science
Year Published: 2023
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