Cancer Immunotherapy A modularized DNA nanodevice agonist (DNDA) is meticulously designed to function as both a nanocarrier and an agonist for cGAS‐STING activation. These innovative DNA‐based multifunctional modules facilitate macrophage‐selective… Click to show full abstract
Cancer Immunotherapy A modularized DNA nanodevice agonist (DNDA) is meticulously designed to function as both a nanocarrier and an agonist for cGAS‐STING activation. These innovative DNA‐based multifunctional modules facilitate macrophage‐selective uptake and programmable STING activation. By effectively altering the immunosuppressive tumor microenvironment, DNDA synergizes with immune checkpoint inhibitors, thereby enhancing anti‐tumor immunotherapy. More details can be found in article number 2400149 by Guiying Li, Lijun Hou, Weihong Tan, Zeyu Xiao, and co‐workers.
Journal Title: Advanced Science
Year Published: 2024
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