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Metabolic Engineering of Corynebacterium glutamicum for High‐Level Production of 1,5‐Pentanediol, a C5 Diol Platform Chemical (Adv. Sci. 13/2025)

Metabolic Engineering of Corynebacterium glutamicum In article number 2412670, Jeong Chan Joo, Jin‐Byung Park, Si Jae Park, and co‐workers highlight the development of a metabolically engineered Corynebacterium glutamicum for sustainable… Click to show full abstract

Metabolic Engineering of Corynebacterium glutamicum In article number 2412670, Jeong Chan Joo, Jin‐Byung Park, Si Jae Park, and co‐workers highlight the development of a metabolically engineered Corynebacterium glutamicum for sustainable production of 1,5‐pentanediol via a lysine‐derived pathway. Through systems metabolic engineering strategies, the final strain produced 43.4 gL−1 1,5‐pentanediol, showcasing systematic approaches to biobased chemical synthesis by microbial cell factories.

Keywords: engineering corynebacterium; corynebacterium glutamicum; metabolic engineering

Journal Title: Advanced Science
Year Published: 2025

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