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A 68-year-old man presented with a history of several months of weakness and weight loss, and was found to be pancytopenic (WBC = 2.02 K/μL, hemoglobin = 8.1 g/dL, hematocrit… Click to show full abstract
A 68-year-old man presented with a history of several months of weakness and weight loss, and was found to be pancytopenic (WBC = 2.02 K/μL, hemoglobin = 8.1 g/dL, hematocrit = 24.4%, platelet count = 23 K/μL). Bone marrow aspiration and biopsy revealed the presence of 45% minimally differentiated blasts with scant, agranular cytoplasm (Image 1A) with coarse, granular, block-like periodic acid-Schiff (PAS) positivity (Image 1B), raising the possibility of acute lymphoblastic leukemia. Flow cytometric analysis revealed that the blasts, gated based
Journal Title: American Journal of Hematology
Year Published: 2018
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