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1. Henter JI, Horne A, Arico M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007;48(2):124-131. 2. U.S. Food and Drug Administration. Center for Drug… Click to show full abstract

1. Henter JI, Horne A, Arico M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007;48(2):124-131. 2. U.S. Food and Drug Administration. Center for Drug Evaluation and Research. Imbruvica NDA 210563/Orig2s000 approval letter. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2018/210563 Orig1s000,210563Orig2s000TOC.cfm. Published February 16, 2018. Accessed April 24, 2019. 3. Fardet L, Galicier L, Lambotte O, et al. Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndrome. Arthritis Rheumatol. 2014 Sep;66(9):2613-2620. 4. McCall CM, Mudali S, Arceci RJ, et al. Flow cytometric findings in hemophagocytic lymphohistiocytosis. Am J Clin Pathol. 2012;137(5): 786-794. 5. Cavallari M, Ciccone M, Falzoni S, et al. Hemophagocytic lymphohistiocytosis after EBV reactivation and ibrutinib treatment in relapsed/refractory chronic lymphocytic leukemia. Leuk Res Rep. 2017;7:11-13. 6. Poole A, Girard N, Clayton F, Tantravahi SK. Rapid onset of hemophagocytic lymphohistiocytosis in a patient with refractory chronic lymphocytic leukemia treated with ibrutinib. Leuk Lymphoma. 2017;58(5):1258-1261. 7. Bergmann K, Moller HEH, Bergmann OJ. Cytomegalovirus-associated haemophagocytic lymphohistiocytosis: a rare cause of febrile neutropenia during cancer chemotherapy. BMJ Case Rep. 2018;2018:bcr2018-225592. https://doi.org/10.1136/bcr-2018-225592. 8. Rao RD, Morice WG, Phyliky RL. Hemophagocytosis in a patient with chronic lymphocytic leukemia and histoplasmosis. Mayo Clin Proc. 2002;77(3):287-290. 9. Papageorgiou SG, Tsiodras S, Siakallis G, et al. Epstein barr virus hemophagocytic lymphohistiocytosis related to rituximab use and immunopathogenetic insights. Pathol Res Pract. 2016;212(12):11941198. 10. Tiong IS, Lau MB, Toumoua S, Chiruka S. A case of hemophagocytic lymphohistiocytosis in a patient with chronic lymphocytic leukemia after treatment with fludarabine, cyclophosphamide, and rituximab chemotherapy, with autopsy findings. Case Rep Hematol. 2012;2012: 326053. 11. Bailey C, Dearden C, Ardeshna K. Haemophagocytic lymphohistiocytosis as a consequence of untreated B-cell chronic lymphocytic leukaemia. BMJ Case Rep. 2017;2017:bcr-2016-219057. https://doi.org/10.1136/ bcr-2016-219057. 12. Kilari D, Venci N, Friedberg J, Bennett JM. Hemophagocytic lymphohistiocytosis masquerading as progressive chronic lymphocytic leukemia. Leuk Res Rep. 2013;2(1):4-6. 13. Merrill SA, Naik R, Streiff MB, et al. A prospective quality improvement initiative in adult hemophagocytic lymphohistiocytosis to improve testing and a framework to facilitate trigger identification and mitigate hemorrhage from retrospective analysis.Medicine. 2018;97(31):e11579. 14. Kohrt HE, Sagiv-Barfi I, Rafiq S, et al. Ibrutinib antagonizes rituximab-dependent NK cell-mediated cytotoxicity. Blood. 2014;123 (12):1957-1960. 15. Ghosh S, Bienemann K, Boztug K, Borkhardt A. Interleukin2-inducible T-cell kinase (ITK) deficiency clinical and molecular aspects. J Clin Immunol. 2014;34(8):892-899. SUPPORTING INFORMATION

Keywords: lymphocytic leukemia; lymphohistiocytosis; hemophagocytic lymphohistiocytosis; chronic lymphocytic; cell

Journal Title: American Journal of Hematology
Year Published: 2019

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