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Loss of surface CD3 expression in allogeneic CAR T‐cells

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F IGURE 1 Allogeneic CAR T-cells in the clinical laboratory. A, B, Peripheral blood smear photomicrographs from patient 1 show CAR T cells in peripheral blood smear with ample cytoplasm… Click to show full abstract

F IGURE 1 Allogeneic CAR T-cells in the clinical laboratory. A, B, Peripheral blood smear photomicrographs from patient 1 show CAR T cells in peripheral blood smear with ample cytoplasm and granules. C, Flow cytometry scattergram from patient one showing an expanded CD8+, sCD3 negative T cell population. D, Flow cytometry scattergram from patient two showing similar CD8+, sCD3 negative T cell population Received: 11 February 2020 Revised: 28 February 2020 Accepted: 2 March 2020 DOI: 10.1002/ajh.25775

Keywords: surface cd3; allogeneic car; loss surface; car cells; car

Journal Title: American Journal of Hematology
Year Published: 2020

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