of disease in pyruvate kinase deficiency and their management. Haematologica. 2020:haematol.2019.240846. https://doi.org/10.3324/ haematol.2019.240846. 5. Necheles TF, Finkel HE, Sheehan RG, Allen DM. Red cell pyruvate kinase deficiency. The effect of… Click to show full abstract
of disease in pyruvate kinase deficiency and their management. Haematologica. 2020:haematol.2019.240846. https://doi.org/10.3324/ haematol.2019.240846. 5. Necheles TF, Finkel HE, Sheehan RG, Allen DM. Red cell pyruvate kinase deficiency. The effect of splenectomy. Arch Intern Med. 1966; 118(1):75-78. 6. Oski FA. Clinical consequences of enzyme deficiencies in the erythrocyte. Ann Clin Lab Sci. 1971;1(2):177-183. 7. Vichinsky E. Non-transfusion-dependent thalassemia and thalassemia intermedia: epidemiology, complications, and management. Curr Med Res Opin. 2016;32(1):191-204. 8. Al-Samkari H, Addonizio K, Glader B, et al. The pyruvate kinase (PK) to hexokinase enzyme activity ratio and erythrocyte PK protein level in the diagnosis and phenotype of PK deficiency. Br J Haematol. 2020. https://doi.org/10.1111/bjh.16724.
               
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