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Granular Mott cells in multiple myeloma

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A 64-year-old woman presented to her general practitioner with a several month history of thoracic back pain. Her blood count showed hemoglobin concentration 112 g/L, WBC 5.6 10/L and platelet… Click to show full abstract

A 64-year-old woman presented to her general practitioner with a several month history of thoracic back pain. Her blood count showed hemoglobin concentration 112 g/L, WBC 5.6 10/L and platelet count 308 10/L. She was found to have an erythrocyte sedimentation rate of 144 mm in 1 hour, an adjusted calcium of 3.02 mmol/L and an IgA lambda paraprotein of 37.3 g/L. Magnetic resonance imaging of the spine demonstrated widespread lytic lesions and pathological fractures of T3 and T4 vertebrae. The bone marrow aspirate showed that normal hemopoietic cells were almost entirely replaced by plasma cells. Many of these could be described as Mott cells since Received: 27 April 2021 Accepted: 1 May 2021

Keywords: mott; hematology; multiple myeloma; cells multiple; mott cells; granular mott

Journal Title: American Journal of Hematology
Year Published: 2021

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