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IMAGE 1 Upper panels: Intermediate to large-sized neoplastic cells present in the peripheral blood smear that were thought to be monocytic blasts on preliminary examination at an outside hospital (Wright… Click to show full abstract
IMAGE 1 Upper panels: Intermediate to large-sized neoplastic cells present in the peripheral blood smear that were thought to be monocytic blasts on preliminary examination at an outside hospital (Wright Giemsa stain, original magnification 500). Middle panels: Flow cytometric analysis reveals the presence of intermediate to largesized neoplastic cells, based on forward light scatter (FSC), that are positive for CD45, T-cell markers CD3 and CD5, and negative for CD2 and CD7. Lower panels: Hypercellular bone marrow biopsy containing approximately 95% intermediate to large-sized neoplastic cells with irregular nuclei, mostly dispersed chromatin, small nucleoli, and small amounts of cytoplasm (left panel; Hematoxylin and Eosin, original magnification 400), that were positive for T-cell marker CD3 by immunohistochemical staining (right panel: original magnification 400) Received: 15 December 2021 Revised: 12 January 2022 Accepted: 13 January 2022
Journal Title: American Journal of Hematology
Year Published: 2022
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