LAUSR

Rituximab is a widely-used medication for many years, important in management of immune thrombocytopenia (ITP); however, the optimal rituximab dose remains unknown. Ni and colleagues report a clinical trial comparing 2 doses of rituximab: a single dose of 375 mg/m2 versus 100 mg/m2 weekly for four weeks. The authors report similar efficacy and safety profile with both strategies. However, single-dose rituximab offered substantial benefits in quality-of-life and decrease in treatment costs. The study by Ni and colleagues adds a new option for management of ITP with rituximab. This article is protected by copyright. All rights reserved.