LAUSR

States of systemic iron overaload, such as hereditary hemosiderosis and iron overload secondary to transfusion dependence, are known to be associated with optic neuropathy. 1 – 3 Similarly, several studies have shown the treatment of such states with chelation therapy, particularly deferoxamine, to be associated with optic neuropathy. 4 – 8 We report a case of optic neuropathy in a patient with hereditary xerocytosis (HX), an autosomal dominant hemolytic anemia that requires frequent and life-saving blood transfusions, which resulted in iron overload treated with chelation therapy. A 28-year-old female with history of HX with transfusion depen-dence on chronic chelation therapy presented with acute, painless, unilateral, and sectoral vision loss during her hospitalization for an epi-sode of symptomatic anemia.