IMAGE 1 A 60-year-old man with femoral bone mast cell sarcoma. The neoplastic cell are large , some are multinucleated, with irregular nuclei, multiple nucleoli and abundant pink cytoplasm. The… Click to show full abstract
IMAGE 1 A 60-year-old man with femoral bone mast cell sarcoma. The neoplastic cell are large , some are multinucleated, with irregular nuclei, multiple nucleoli and abundant pink cytoplasm. The tumor cells expressed tryptase, CD117, CD33, CD30, and a small subset showing weak CD123 (arrows). They were negative for CD25 and CD2. KIT D816V mutation was not detected. KRASG12C detected Received: 16 February 2022 Accepted: 28 February 2022
               
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