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Vitamin D and folate: A reciprocal environmental association based on seasonality and genetic disposition

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The purpose of this study was (1) to elucidate any reciprocal seasonal relationship that might exist between red cell folate (RCF) and serum vitamin D3 Levels; (2) to explore whether… Click to show full abstract

The purpose of this study was (1) to elucidate any reciprocal seasonal relationship that might exist between red cell folate (RCF) and serum vitamin D3 Levels; (2) to explore whether folate‐related gene variants that influence/alter DNA‐thymidylate and methyl group biosynthesis modify any associations detected in objective 1; and (3) to consider whether these processes might influence reproductive success consistent with the “folate‐vitamin D‐UV hypothesis of skin pigmentation” evolutionary model.

Keywords: vitamin folate; reciprocal environmental; folate; folate reciprocal; environmental association; vitamin

Journal Title: American Journal of Human Biology
Year Published: 2018

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