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A facile, elegant, and operationally simple van Leusen protocol for the synthesis of bicyclic dihydrodibenzo[b,f]imidazo[1,2-d][1,4]thiazepines and dihydrodibenzo[b,f]imidazo[1,2-d][1,4]oxazepines is developed. The reaction proceeds without any catalyst and in high yields to provide… Click to show full abstract
A facile, elegant, and operationally simple van Leusen protocol for the synthesis of bicyclic dihydrodibenzo[b,f]imidazo[1,2-d][1,4]thiazepines and dihydrodibenzo[b,f]imidazo[1,2-d][1,4]oxazepines is developed. The reaction proceeds without any catalyst and in high yields to provide bicyclic imidazo-dibenzothia-/oxazepines at room temperature by using dibenzothiazepines or dibenzoxazepines as imine counterparts.
Keywords:
van leusen;
leusen protocol;
facile construction;
construction imidazo;
imidazo
Journal Title: Asian Journal of Organic Chemistry
Year Published: 2017
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Journal Title: Asian Journal of Organic Chemistry
Year Published: 2017
Link to full text (if available)
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recommendations!