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Copper(I)‐Catalyzed Cascade Dearomatization of Tryptophols with 3‐Indolylphenyliodonium Salts

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A copper(I)-catalyzed intermolecular cascade dearomatization reaction of 2-substituted tryptophols with 3-indolylphenyliodonium salts has been developed. This approach provided a direct and general access to versatile furoindolines with two quaternary stereogenic… Click to show full abstract

A copper(I)-catalyzed intermolecular cascade dearomatization reaction of 2-substituted tryptophols with 3-indolylphenyliodonium salts has been developed. This approach provided a direct and general access to versatile furoindolines with two quaternary stereogenic centers in good to excellent yields under mild reaction conditions.

Keywords: indolylphenyliodonium salts; tryptophols indolylphenyliodonium; copper catalyzed; cascade dearomatization

Journal Title: Asian Journal of Organic Chemistry
Year Published: 2017

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