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Synthesis of Polycyclic Amides via Tandem RhIII‐Catalyzed C−H Activation and Annulation from Dioxazolones and Alkynes

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A highly efficient synthesis of polycyclic amides by Rh(III)-catalyzed cascade cyclization of 3-phenyl-1, 4, 2-dioxazol-5-one and diphenylacetylene has been developed. This novel one-pot strategy expanded the application scope of directing… Click to show full abstract

A highly efficient synthesis of polycyclic amides by Rh(III)-catalyzed cascade cyclization of 3-phenyl-1, 4, 2-dioxazol-5-one and diphenylacetylene has been developed. This novel one-pot strategy expanded the application scope of directing groups to dioxazolones.

Keywords: amides via; polycyclic amides; synthesis polycyclic; via tandem; tandem rhiii; rhiii catalyzed

Journal Title: Asian Journal of Organic Chemistry
Year Published: 2017

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