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Recent developments of N-heterocyclic carbenes (NHCs)- catalyzed acyl-anion equivalent (Stetter reaction), homoenolate and enolate reactions with reactive nitroalkene as a Michael acceptor are described. Systematically, a unique strategy for NHC-catalyzed… Click to show full abstract
Recent developments of N-heterocyclic carbenes (NHCs)- catalyzed acyl-anion equivalent (Stetter reaction), homoenolate and enolate reactions with reactive nitroalkene as a Michael acceptor are described. Systematically, a unique strategy for NHC-catalyzed C-C bond formation reactions using nitroalkenes for the synthesis of synthons are presented, particularly in asymmetric approach. Advances in the single-electron-transfer (SET) reaction merging with NHC as an organocatalyst are also discussed with nitroalkenes as important coupling partners. This review attracts both the accomplishments and the future works needed in this important area.
Journal Title: Asian Journal of Organic Chemistry
Year Published: 2018
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